Imaging for Body Composition Trials: Opportunities and Considerations
Imaging for Body Composition Trials: Opportunities and Considerations
January 30, 2025
10:00 am ET
The development of new treatments for body composition disorders is evolving and so is the advancement of imaging biomarkers. Though quantification of muscle and fat is not new, the options available to delineate and quantify muscle and lean mass are getting more sophisticated these days, leaving many sponsors with questions about how to best define their clinical trial endpoints.
Determining which imaging modality, anatomical coverage, and analysis methods to use can be critical to your trial outcomes. As the field explores new ways of deriving endpoints and exploring trends to support decisions, it is also prudent to appreciate what are the standard and validated endpoints that can be obtained based on the imaging modality.
Join us while our body composition imaging experts review the imaging modalities and analysis methods currently available to quantify body composition, including the benefits and limitations of the various options in the context of multi-center clinical trials.
Presenters:
Sally Warner, PhD, VP, Scientific and Medical Services, Perceptive
As the Therapeutic Area Lead of Perceptive Musculoskeletal Imaging, Dr. Warner applies her 25+ years of medical imaging research experience and the expertise she’s gleaned from supporting imaging services for over 200 clinical trials to help pharmaceutical companies and CROs succeed. Dr Warner’s musculoskeletal research has included the use of many different modalities (DXA, MRI, CT, hydrostatic weighing and bioelectrical impedance) for the assessment of body composition. She is a faculty member with the International Society for Clinical Densitometry helping define and deliver standardized training to DXA technologists, particularly for whole body scanning.
Farhan Syed, PhD, Medical Director, Perceptive
As a director working in the Musculoskeletal therapeutic area Dr. Syed and has over 20 years’ experience in the field. He applies his extensive training and knowledge in bone loss mechanisms and imaging ‒ both in pre-clinical and clinical settings ‒ to leading and overseeing varied clinical trials involving the musculoskeletal system. He trained as a post-doctoral fellow at the Mayo Clinic in Rochester and was subsequently a Research Assistant Professor in the Kogod Center of Aging at Mayo Clinic based in Rochester where his area of research was focused on mechanisms of bone loss and changes in body composition utilizing pre-clinical and clinical models. He has over 40 publications / presentations and has authored numerous review articles and book chapters in this area. He also serves as a subject matter expert, contributing and facilitating protocol reviews as well as imaging-focused discussions with clients as well as consultation and networking with Key Opinion Leaders in the field.
