Calyx and Invicro are now Perceptive
Independent review of trial event assessments by adjudication experts.
Proven expertise in delivering high-quality imaging data at a global scale.
With strengths in instrument engineering, signal processing, and pharmaceutical R&D, Perceptive Discovery consistently delivers successful imaging study designs and executions.
Effective RTSM, built on 30 years of experience, and connected to an ecosystem which includes eConsent and eCOA.
Highly established imaging centers for first-in-human and multicenter trials.
900+ agents radiolabeled and counting.
Supporting both malignant and non-malignant indications.
Experts in Alzheimer’s Disease, Parkinson’s Disease imaging and more.
Supporting over 85% of radiopharmaceutical companies.
Optimize preclinical and clinical trials in other areas and drug classifications.
Therapeutic and technical expertise in imaging modalities, protocol design, and acquisition.
Oncology imaging, RTSM, and clinical adjudication services.
Tackling unique rare disease trial supply, imaging and adjudication challenges.
We are here to serve science.
From discovery, through early to late-phase clinical development, to regulatory approval and post-market, you can count on Perceptive to be dependable, diligent, and driven in everything we do.
Perceptive Discovery bridges preclinical insights to early clinical success, ensuring rigorous scientific analysis and high-quality data to support innovation.
Providing the right-fit randomization & trial supply management solution for your trials, delivered by experts.
The right people, experience, and technology to drive clinical trial imaging success.
Flexible, right-fit eClinical solutions, backed by unmatched experience and expertise. Delivered by a dedicated and skilled team that supports you every step of the way.
Clinical trials
Participants randomized
Regulatory approvals
Orphan drug regulatory approvals
Countries globally
On-time delivery
We offer unmatched depth and breadth of therapeutic area IRT/RTSM expertise, offering valuable insights and real-world operational experience.
Our flexible eClinical solutions ensure a right-fit approach, combining speed and intuitive design. We prioritize quality, data integrity, and innovation, supporting you to reach your clinical goals.
Delivery speed
Integration partners
Integration files sent daily
System uptime
From simple to stratified, adaptive to dynamic, list creation to data release, our randomization expertise has you covered.
Visualize your results with randomization simulation, and confidently advance your clinical trial with the right methodology.
We deliver RTSM solutions that simplify your clinical trial management while maintaining the highest standards of accuracy and quality.
Ensure minimal monitoring effort and automatic site supply, tailored to ongoing participant needs.
Make changes when it suits you—adjust site data, cap enrolment, or add new countries, doses, or cohorts quickly and conveniently.
Configurable, pre-validated solutions save time, enhance quality, and adapt to changing study dynamics.
Strict, robust blinding controls protect the integrity of your trials, tailored to your study’s unique risks.
Our intuitive system design ensures you always have access to the data you need, precisely when you need it. From reducing failed visits to managing limited drug availability, we recommend the best RTSM setup to meet your key measures. The right treatment, for the right participant, on time, every time.
We work toward common goals, providing tailored support with integrity throughout your clinical development journey.
Site satisfaction results
In-house help desk
Languages supported
Software security. It’s in our DNA.
Pre-identified risks in our library
Our in-house 24/7 help desk is dedicated to resolving site and patient issues. With specialized teams and local language support.
Project delivery and support across North America, Europe, Asia-Pacific, and Africa.
We start with our library of over 200 risks, then actively tailor the risk management plan according to your protocol and our experience delivering and supporting over 2,700 clinical trials.
Our commitment to being a sustainable RTSM supply chain partner.
Costly trial supplies – benefit from a range of advanced methods to reduce the supplies sent to site, from the recruitment phase to the last visit cycle.
Sourcing changes – change standard of care sourcing at both IMP and site levels, with automatic changes to site resupply strategy.
Disease progression – be assured that the system is designed from the start to manage additional participant visits.
Dose calculations – can be performed by the IRT if of value to sites, using any dose calculation and any formula.
Complex visit schedule – the system can be tailored to apply any protocol rules for switching between and restarting schedules.
Rescue medication – let RTSM mitigate the unknowns of treatment pause, including optimizing supplies and expiry management.
Novel randomization – from enrolment-only design to adaptive techniques, we are experts in approaches you can use to reduce the overall number of participants a rare disease trial requires.
Expensive and/or limited drug supply – use advanced methods to ensure only what’s needed is sent to site, including automatic site resupply tailored to recruitment rate and participants characteristics.
Long recruitment period – be assured by built-in self-service flexibility, customizable reporting, and ongoing dedicated support for the life of the trial.
Challenging logistics – let the system manage tight controls on the participant-led supply chain, from manufacturing to time windows and expiry.
Fast-paced recruitment – easy-to-use recruitment controls with multi-level capping and site resupply tailored to manage a higher risk of stock-out.
Seasonal recruitment – benefit from automatic site resupply tailored to the season, plus advanced expiry management controls to best manage short shelf-life.
Short turnaround for design changes – we anticipate the need for fast adaptation with built-in flexibility to add new cohorts and doses.
Quality data needed promptly – rely on a system designed with data quality in mind, plus customizable reports and data sets to allow you to meet tight review timelines for cohort studies.
Sub-set randomization – can be effectively managed by RTSM, including randomization at the visit when data is needed to ensure drop-outs do not affect sub-set treatment balance.
Personalized drug manufacture – RTSM can support a complex and participant-led supply chain, including manufacturing slot and delivery verification, reserved medication, and personalized shipments.
Short time windows – let RTSM manage rapid timeframes, including time to participant administration and expiry management to the hour.
Complex visit management – RTSM can support personalized treatment plans, infusion volume calculations, and effective cross-team communication and alerting on upcoming events.
Innovative trial designs – rely on our experience of a range of innovative designs, including adaptive trials. Our support of master protocols includes a range of options for medication pooling, from the simple to the complex.
High risk of unblinding – we are experts at mitigating unblinding risk throughout the life of the trial, from randomization to site shipments to drug allocation to data provision. Our cross-functional SME team will deliver a tailored risk plan to ensure the additional unblinding risks of individualized treatment are properly managed.
We give your clinical trial teams easy insight into key aspects of their trial, including:
Whether you need to optimize your resupply to reduce waste, reduce shipments, or improve your carbon footprint, our expertise can support you in meeting your goals.
Every study has a dedicated Project Manager for the life of your trial supported by a team of RTSM specialists, allowing us to anticipate and quickly resolve challenges that might jeopardize your study milestones.
Average experience of our RTSM consultants
Average experience of our client-facing team
Built-in design adaptations
Cohort studies
Successfully delivered adaptive designs
Reduction on IMP pooling across programs
Reduction on IMP waste
Kits dispensed per minute
Reduce the burden of monitoring site stock by automatically adapting the amount of medication shipped to sites based on the number of patients in screening.
Limit overage with our advanced prediction algorithms.
Reduce drug wastage and address availability concerns by pooling supplies across different protocols in a single program.
Reduce waste by sending medication to each site specific to upcoming treatment group assignments.
Estimate study supply needs using advanced simulation modeling.
We are accountable and reliable, delivering 100% of studies on time for the first patient.
Seamless integration across all eClinical, CRO, depot, and laboratory vendors.
Leverage operational insights from over 2.7 million enrolled participants to keep your trials on track.
With our 24/7/365 in-house help desk, we’re always ready to meet your challenges.
With a 99.9% system uptime, you can rely on our platform to support your clinical trial needs.
We’re proud to support science with over 500 regulatory approvals, including 150 orphan drug approvals.
Minimize data reconciliation with RTSM designed for first-time quality, with real-time guidance and data validation to authorize data changes.
Although IRT & RTSM are used interchangeably to refer to critical clinical trial technology, put simply – IRT is what it is (Interactive Response Technology) & RTSM is what it does (Randomization and Trial Supply Management). Advanced IRT can do so much more to support you & your trial than its core of RTSM.
There is so much to consider when deciding which IRT/RTSM vendor to trust with your trial. What’s essential for you to consider when selecting a vendor who can support the successful implementation of your trial, includes both the technology and the people.
You should expect your IRT vendor to enable randomization, to manage trial supplies and to design for data quality. A good vendor has the technology and the experience to support all trial designs, including cohort and adaptive trials, provide expert guidance on randomization methodologies, automatically optimize site resupply and integrate seamlessly with any system.
When selecting an IRT/RTSM vendor, you should consider how they can support the successful execution of your trial. A technology-enabled service provides expertise to manage your challenges, experience to implement your trial design, flexibility to meet any of your protocol & packaging needs and the adaptability to manage planned and unplanned changes.
You should expect an RTSM system to get the right drug to the right participants on time, every time. By using advanced inventory management for your trial, you can also automatically reduce drug wastage, carbon footprint, and site supply monitoring effort.
Designing an optimal IRT/RTSM system for clinical trials requires a comprehensive approach, which includes the following key areas: protocol design, study goals, risk management, ease of use, flexibility and adaptability for the life of the trial.
RTSM experts can help you understand if a randomization methodology is right for your trial. With early engagement, they can provide consultancy to plan the implementation of your novel method.
By integrating data from a range of systems, including laboratories, trial supplies & EDC, an IRT can help reduce duplicate data entry, manage unblinding risks and automate tasks.
Reach out today and one of our solution experts will be in touch to learn about your specific needs.
