Preclinical Imaging
With strengths in instrument engineering, signal processing, and pharmaceutical R&D, Perceptive Discovery consistently delivers successful imaging study designs and executions.


Harness advanced imaging for faster, more informed decision-making.
Generate early data to support your research initiatives with Perceptive Discovery’s best-in-class preclinical imaging services. Our seamless approach across early-phase R&D saves you time and ensures consistency, helping you to identify the most promising compounds and minimize risk.
15+
Years of experience
Over 3K
Studies supported
8
Preclinical labs
Trusted partner offering radiochemistry, custom experimental design, execution, and results interpretation.
Adaptable approach to specialized imaging biomarker studies.
Multiple imaging facilities and strategic collaborations ensure agile study management and expanded capabilities.
Focus on collaboration ensures consistent growth, fostering long-term partnerships with sponsors.
Bespoke image analytics, pipelines, and cutting-edge tools deliver precise, tailored insights for sponsors.
Key Therapeutic Areas
Perceptive Discovery has vast preclinical experience supporting Neuroscience drug development. Our functional and molecular imaging solutions are well-suited for non-invasive longitudinal studies to provide multiple readouts, such as:
- Biodistribution
- Target engagement and occupancy
- Neuropharmacodynamics
- Neurotransmitter release
- Biological therapeutics pharmacokinetics
- Neuroinflammation
- Neuromodulator analysis
We use state-of-the-art imaging techniques to characterize the behavior of novel therapies and identify imaging biomarkers across diverse tumor model types (e.g. subcutaneous, orthotopic, metastatic).
Our core capabilities include:
- Biodistribution of test articles
- Target density and engagement
- Pharmacokinetics (PK)
- Pharmacodynamics (PD)
- Tumor growth properties
- Therapeutic efficacy
Perceptive partners with sponsors to advance radiopharmaceutical therapy from proof-of-concept through late-phase trials. Our preclinical expertise in primary in vivo pharmacology services, radiochemistry, biodistribution, and dosimetry services supports optimized therapy development and accelerates progress toward first-in-human studies.
Our core capabilities include:
- Proof-of-concept studies to evaluate tumor targeting and anti-tumor activity
- Radiolabeling and immunoreactivity method development for alpha, beta, and gamma isotopes
- Biodistribution and dosimetry studies using imaging, gamma counting, and advanced analyses
- Tailored clinical trial strategies focused on radiation safety, dosimetry, and patient selection
Modalities and Models
Perceptive Discovery offers an array of preclinical services that deliver high-fidelity data and actionable insights to support informed decision-making.
From the intricacies of molecular processes to the complexity of whole-body systems, we are committed to harnessing the power of advanced technologies to develop imaging biomarkers, ensuring every study is equipped with the tools necessary.
We utilize a comprehensive range of animal models to ensure translational relevance, from small rodents to non-human primates (NHPs). These models are meticulously chosen, developed, and managed to provide relevant and translatable data across therapeutic areas.
Expert Radiochemistry Services for Preclinical and Translational Studies
Radiolabeled compounds enable non-invasive evaluation of drug distribution, metabolism, and pharmacokinetics through PET and SPECT. Perceptive’s expertise in optimizing and synthesizing radiolabeled compounds ensures preclinical imaging studies are conducted with scientific rigor, accuracy, and safety, driving more efficient drug development.
Image Analysis
Perceptive’s medical image analysis team specializes in developing advanced algorithms and pipelines to tackle complex image science challenges, extracting precise quantitative data for studies ranging from discovery research to late-phase clinical trials.
By combining the latest advancements in image science with engineering expertise, we innovate and refine new algorithms and automated and semi-automated image analysis processes to ensure efficient, reliable analysis.
We support a range of preclinical image analysis tasks, tailoring our approach based on the species, imaging modalities, and therapeutic focus. Using our in-house software, including VivoQuant and iPACS, we apply existing tools or develop new ones to meet the specific needs of each study while offering sponsors convenient access to image data and results.
VivoQuant: Advanced Image Processing and Analysis Software for Early Drug Development
VivoQuant is a powerful, vendor-neutral imaging software designed to deliver seamless image post-processing and analysis across multiple modalities and species. Engineered through collaboration with scientists, for scientists, VivoQuant empowers researchers by combining fundamental viewing functionality with powerful tools for fine-tuning images and isolating and analyzing regions of interest for quantitative analysis tailored to preclinical workflows.
From Bench to Bedside: Discover Our In-House Imaging Clinics
With Perceptive’s translational imaging expertise, sponsors benefit from coordinated imaging protocol development across preclinical and first-in-human clinical studies.
Our streamlined approach saves time, reduces complexity, and supports regulatory success by delivering high-quality data and insights across translational research. Discover how our in-house imaging clinics in New Haven and London can advance your program.
Discover Our Clinical Trial Imaging Solutions
In-House Clinical and Imaging Centers
Highly established clinical and imaging centers supporting first-in-human and multicenter studies.
Imaging Core Lab
Proven expertise in delivering high-quality clinical trial imaging data at a global scale.