Imaging
Core Lab

Proven expertise in delivering high-quality clinical trial imaging data at a global scale.

When you need to drive efficiency and high-quality data across small and large-scale clinical trials, Perceptive’s Imaging Core Lab has you covered.

We combine deep medical and operational expertise to deliver clinical trial imaging biomarkers across key therapeutic areas such as oncology, neuroscience, and radiopharmaceutical therapy.

110,000+

Qualified imaging sites and centers across the globe

3,400+

Clinical trials supported

650+

Expert reader network

350+

Regulatory approvals supported

Capabilities by Therapeutic Area

Neuroscience

From first-in-human studies to Phase IV global studies, Perceptive is the world’s leading CNS imaging solution provider.

  • 650+ neuroscience imaging studies, including 340+ Alzheimer’s disease clinical trials and 100+ Parkinson’s clinical trials, and specialty rare disease areas like sickle cell and adult-onset leukoencephalopathy (ALSP)
  • Global access to qualified imaging centers and clinics, including two in-house imaging clinics with PET, SPECT, and MRI capabilities
  • Advanced MRI: validated and exploratory analysis pipelines including Volumetrics, DTI, fMRI, neuromelanin, MRS
  • PET analysis: validated and novel approaches including SUV generation and centiloid mapping as well as AmyloidIQ and TauIQ

Oncology

Perceptive is a trusted partner in oncology imaging, having supported over 2,000 clinical trials across solid tumor and hematological malignancy indications.

Validated Criteria Examples

  • PERCIST
  • RECIST 1.0/1.1
  • PCWG 2.0/3.0
  • RANO, RANO-BM
  • mRECIST
  • LUGANO
  • IMWG
  • IWCLL
  • IWWM
  • International Pediatric
  • NHL Response Criteria

Modified for Immuno-oncology

  • iRECIST
  • irRECIST
  • LYRIC
  • IrRC

Our image analysis team also specializes in developing and applying a broad range of tools to support advanced quantitative oncology tracer characterization and analytics across numerous clinical trial imaging modalities and studies including dosimetry services and biomathematical modeling.

Radiopharmaceutical 
Therapy & Theranostics

Having supported over 85% of radioligand therapy (RLT) and theranostics companies, Perceptive is the leading service provider for radiopharmaceutical development.

  • First-in-human, single-site clinical trial support
  • Study design consultation
  • Criteria-based centralized independent reviews and internal analysis
  • Global multi-center clinical trial support with response criteria reads
  • Image analytics including FDG-PET analysis, dosimetry, tumor segmentation, and radiomics
  • Safety profile and therapeutic efficacy studies

Musculoskeletal

When tackling the many challenges involved in Musculoskeletal (MSK) trial imaging, global clinical trial sponsors repeatedly turn to Perceptive for the right experience, people, processes, and technology to drive their MSK development program’s success.

  • Supported over 360 MSK trials, many having led to regulatory approvals
  • Experience across a breadth of MSK indications:
    • Supported over 20 Axial Spondyloarthritis trials, utilizing criteria like Modified New York Score, ASAS OMERACT MRI Score, and SPARCC for Spine and SIJ.
    • Delivered clinical trial imaging expertise for 60+ Rheumatoid Arthritis and Psoriatic Arthritis trials, employing scoring methods such as RAMRIS, PsAMRIS, and Sharp Scores.
    • Successfully supported 35+ Osteoarthritis trials, employing assessments such as Joint Space Width, KL Grading, and advanced cartilage and bone assessments.
    • Extensive experience in 70+ Osteoporosis trials, providing imaging solutions like DXA-derived T and Z-scores, QCT-based analysis, and bone quality.
    • Worked on imaging for rare MSK diseases like Duchenne Muscular Dystrophy, SMA, and Gaucher’s disease, leveraging tailored protocols and close collaboration with global KOLs.
      Learn more about our experience in these MSK indications: Rheumatology, Women’s Health / Endocrinology, Metabolic / Body Composition, Rare Disease

Hematology

Having supported over 360 hematology trials across malignant and non-malignant conditions, Perceptive combines deep expertise and global collaboration to support every stage of hematology clinical trials, from thorough protocol consultation to regulatory success:

  • Proven ability to deliver on tight timelines without compromising data quality
  • Extensive experience in hematology trials with global regulatory approvals including NMPA
  • Broad KOL network featuring renowned advisors and internal experts
  • Expert protocol consultation
  • 24/7 support for seamless communication and issue resolution
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Complete Project Support Process

Perceptive offers proactive, collaborative study management and
scientific support to ensure seamless, timely execution of clinical imaging core lab workflows:

1. Study Design

Leverage scientific and regulatory expertise to develop tailored imaging protocols.

2. Study Start-Up

Site training, investigator meetings, and qualification for standardized trial readiness.

3. Image Management

21 CFR Part 11 compliant platforms for submission, quality control, and data tracking.

4: Read Management

Subspecialty readers ensure consistent, expert image assessments.

5. Image Analysis

Advanced analytics and validated workflows for modality-specific insights.

6. Data Management

Regulatory-compliant data delivery for efficient submissions.

7. Study Closure

Final data transfer including images and minutes.

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Reader Programs

Perceptive partners with leading institutions to select subspecialty radiologists, neuroradiologists, and oncologists for our reader programs.

We have a dedicated team that qualifies and selects readers to ensure that we have the most experienced professionals available and trained according to your specific project needs. Reads can be performed either as rolling reads as time points come in or batched and read as subjects come off study.

Additionally, with our expert team of in-house board-certified radiologists and oncologists delivering consistent evaluation, we’re able to ensure the highest standards of image and clinical data analysis. We leverage various reviewer performance monitoring methods and adhere to rigorous quality control processes with independent blinded image and clinical data reviews to support innovative treatments.

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Global Reach

Your work is global and so are we. With local support in China, India, Europe, and North America, you can have confidence that your research and clinical trials will run smoothly and deliver high-quality data you can rely on every time.

Our client delivery teams anticipate your needs and scale our services to deliver quick and reliable continuity of service, ensuring efficient site setup to meet your timelines and providing dedicated teams for quality control support.

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“We’re pleased to partner with [Perceptive] and are confident that 
our customers will benefit from the scientific, medical, and clinical expertise they have honed during 
their 30 years of delivering reliable eClinical solutions to the clinical development industry.”

Christy MeyerDirector/Quality Assurance. ProTrials

How Can We Help

Reach out today and one of our solution experts 
will be in touch to learn about your specific needs.